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Norgren et al., evaluated 5,093 Scandinavian soldiers to determine risk factors in producing back pain and clearly demonstrated that decreased spinal range of motion, particularly segmental mobility correlated with tenderness, was a predisposer to the increased incidence and severity of low back pain. These studies clearly support the idea that global and therefore segmental hypomobility is a predisposer and precursor to increased injury and disability.

Norgren B, Schele R, Linvooth K. Evaluation and prediction of back pain during military field service.
Scand J Rehab Med 1980: 12: 1-8

The flip side of this equation is demonstrated in the Meade et al., study in which it was clearly demonstrated that in those low back pain patients who received chiropractic manipulation, and therefore attained documented superior restoration of mobility or increased global (and therefore segmental) mobility (as opposed to the control group of physical therapy patients), the chiropractic patients had less reoccurrences and complications, less need of additional treatment, and less disability.  

Meade TW, Byer S, Browne W, Townsend J, Frank AO. Low Back Pain of Mechanical Origin: Randomised Comparison of Chiropractic and Hospital Outpatient Treatment
British Medical Journal 1990 (Jun 2); 300 (6737): 1431–1437